individual is inflicted by gigantism, it is the endocrine system that is being affected. Because it is the endocrine system that regulates the secretion of hormones in the body, it directly affects just about every other system in our bodies. From the reproductive system to the digestive system, it is the hormones released by the endocrine system that make everything function the way it is supposed to.
The growth hormone has two main functions when it comes to regulating various bodily functions in adults. It has both direct and indirect effects. To begin with, growth hormone, which is part of the endocrine system, binds onto receptor cells on the body part that it will directly affect. For example, the growth hormone will bind onto the fat cells which have growth hormone receptors, in order to make them function and break down triglyceride and suppress their ability to take up and…...
mlaReferences:
Melmed S, Kleinberg D., Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. (2008) Anterior pituitary. In: Williams Textbook of Endocrinology. 11th ed. Philadelphia, PA: Saunders Elsevier; Chapter 8.
Rosenfalck A.M., Fisker, S., Hilsted, J., Dinesen, B., Volund, A., Jorgensen, J.O., Christiansen, J.S., & Madsbad, S. (1999). The effect of the deterioration of insulin sensitivity on beta-cell function in growth-hormone-deficient adults following hormone replacement therapy. Growth Hormone & IGF Research, 9(2), 96 -- 105.
Waters MJ, Kaye PL. (2002) The role of growth hormone in fetal development. GH and IGF Res 12:137-146
Bellone S, Rapa A, Vivenza D, Castellino N. et al. (2002) Circulating ghrelin levels as a function of gender, pubertal status and adiposity in childhood. J Clin Endocrinol Investigation 25:RC13-15.
" This drug has already won approval for use in Europe and the United tates. tudies conducted show that the drug "targets the tumor to control in four areas: in the site where hypersecretion starts, in GH secretion, IGF-1 and in the symptoms associated with the disease (Unknown, 2004)." While the drug has been approved, there are still contraindications to taking it such as a patient who has an irregular or slow heart rate, or blood sugar levels which are either too high or too low.
Occurrence
Although gigantism begins prior to puberty, the "majority of giants eventually demonstrate features of acromegaly, of which the mean age for the onset is within the 3rd decade of life. Even a congenital onset of GH excess has been suggested by linear growth acceleration occurring within the first few months of life in young children with documented gigantism (http://jcem.endojournals.org/cgi/content/full/84/12/4379)." Although there is no accurate number…...
mlaSimmons, Kirt E. (01 October, 1999). "Growth Hormone and Craniofacial Changes: Preliminary Data From Studies in Turner's Syndrome." Pediatrics.
Skatssoon, Judy. (21 May, 2002). "NSW: New discovery could lead to cure for dwaftism, gigantism." AAP General News (Australia).
Unknown. (01 June, 2004). "Novartis Sandostatin LAR approved in Japan for Acromegaly. Worldwide Biotech.
For instance a patient suffering from hypotonia may receive physical therapy to assist them in gain more control over bodily movements. Likewise an individual with Sotos syndrome that has been diagnosed with ADD may be treated with behavioral counseling and medications. Behavioral therapies may also be needed to combat aggressiveness, develop social skills, combat tantrums and some personality disorders that may be present. The mental retardation that can occur as a result of Sotos may be treated with learning therapies and through special education. Also language delay may be treated with speech therapy.
Individuals that develop tumors and cancer as a result of the disorder may be treated with surgery, radiation or chemotherapy. Likewise those with heart defects or kidney problems may need surgery or dialysis. Medical treatments may also be necessary as it relates to any skeletal malformations that may persist into adulthood as some researchers have reported that…...
mlaReferences
Finegan, J.K.,Cole, Trevor R.P.;Kingwell, E.,Smith, M. Lou;Smith, M.,;Sitarenios, G. (November 1994) Language and behavior in children with Sotos syndrome. Journal of the American Academy of Child and Adolescent Psychiatry
Hglund, P., Kurotaki N., Kytl S., Miyake N., Somer M., Matsumoto N. (2003)
Familial Sotos syndrome is caused by a novel 1 bp deletion of the NSD1 gene. J Med Genet 2003; 40:51-54
NINDS Cephalic Disorders Information Page. Retrieved August 11, 2007 from;
What is the most likely diagnosis?
John is believed to be suffering from gigantism or acromegaly.
Symptoms of acromegaly
The term 'acromegaly' has its roots in the Greek terms for "enlargement" and "extremities"; these terms reflect one among the ailment's most commonly occurring signs of abnormally expanding feet and hands (Marieb & Hoehn, 2018a; 2018b). Swollen feet and hands typically manifest as an initial sign. Those suffering from the acromegaly notice changes in their shoe or ring sizes, especially shoe width. Slowly, changes in the bone begin to transform their facial features, with their lower jaw and brow protruding, spacing out of the teeth, and enlargement of their nasal bone (Colao et al., 2019).
Abnormal cartilage and bone growth frequently results in arthritis. Tissue thickening can trap nerves and result in the development of carpal tunnel syndrome (CTS) that in turn produces weakening and numbness of hands. Enlargement may also occur in the heart…...
S. Congress that the prospects of stem cell research were so vast that it could touch all the realm of medicine (Connor 2000). An unlimited source of embryonic stem cells will solve the problem of shortage of transplants. Embryonic stem cells will save lives by curing generative diseases of the brain, hepatitis, diabetes, leukemia, rheumatoid arthritis, muscular dystrophy and cystic fibrosis and diseases of the heart and kidneys. ut current laws restrict the use of stems cells on embryos less than 14 days old and for correcting fertility, reproduction or congenital disorders. The restriction is grounded in the belief that the embryo is a potential human being from the moment of conception. It thus possesses a soul and a dignity just like any other viable person (Connor). Previous scientific research presented evidence that genetically engineering cells could partly repair a defective immune system (Travis 2002). Two new studies bolstered this…...
mlaBibliography
Bauer, D.G. (2005). Review of the endocrine system. MedSurg Nursing: Jannetti Publications, Inc.
Connor, S. (2000). Science: the miracle cure with a catch. The London Independent: Newspaper Publishing PLC
Degen. D (2008). Body organization and homeostasis. 1 page. Bones, Muscles and Skin. Pearson Education, Inc.: Pearson Prentice Hall
Farabee, M.J. (2006). Animal organ systems and homeostasis. 18 web pages. Estrella Mountain Community College. Retrieved on February 1, 2006 at http://www.emc.maricopa.edu/faculty/farabee/biobk/BioBookMUSSKEL.html
Unlike Frey, Arleo states: "it is the face that most intrigues and challenges me. During the twenty years that I've worked with the figure, the faces have moved steadily from vagueness toward increasing specificity and recognizability. The eyes, when I was starting out, were undefined; they have since evolved from being closed, to being downward turned, to being open and forthrightly gazing."(Arleo, 2006) Arleo's sculptures, often also in clay, are more human in their scope and their appearance, and invite a kind of intimacy between gazer and crafted work.
orks Cited
Arleo, Adrian. orksGalleryArtists Commentary by the artist. [28 Nov 2006] http://www.snyderman-works.com/works/artists/ceramics/arleo/arleo.html
Gilmore, Jonathan. "Viola Frey at Nancy Hoffman - ceramic figures at Nancy Hoffman Gallery, New York."Art in America. June 2002. [28 Nov 2006] http://www.findarticles.com/p/articles/mi_m1248/is_6_91/ai_102793137...
mlaWorks Cited
Arleo, Adrian. WorksGalleryArtists Commentary by the artist. [28 Nov 2006] http://www.snyderman-works.com/works/artists/ceramics/arleo/arleo.html
Gilmore, Jonathan. "Viola Frey at Nancy Hoffman - ceramic figures at Nancy Hoffman Gallery, New York."Art in America. June 2002. [28 Nov 2006] http://www.findarticles.com/p/articles/mi_m1248/is_6_91/ai_102793137
e see therefore that sensations and sensibilities work hand-in-hand as thought processes work together with the affective domain like partners in a dance. A balance or equilibrium is attained where the heart and mind intersect, where beneficial decisions are made, such as whether to satisfy a hunger that is necessary for living, or just a craving that can make one obese.
The sense of hunger like any living sensation is a biological calling for survival. hen one needs to energize, one has to fuel up with some supply of calories and for living things, it is called food. Here we see that what captures the senses, whether they are grounded on necessity or excess, is the first encompassing attracting element of any advertising campaign.
Until now McDonalds advertisements evoke the sense of fulfilling one's basic needs such as food that can be conveniently accessed and attained with ease because of a…...
mlaWorks Cited
The Editors of Publications International, Ltd. 8 Memorable Advertisement Campaigns.
Howstuffworks. 1998-2009.
The use of the cowboy as the main symbol of the brand responded to the needs that people had at those times. It was a figure who stood for authenticity.
In addition, its complexity derived from the fact that being nonetheless a "real" person, older, wrinkled, it had style and class. In addition, it was a character who took complete control of the things in his life and this was appealing for everyone. People wanted to be like the cowboy. Strong and free. It was a long way from the may feel that the Marlboro cigarettes started out with.
The example that has been analyzed in this paper demonstrates how powerful image can be. The Marlboro cigarettes themselves have surely underwent a process of technological development regarding filters, the quantity of nicotine they include, their chemical composition, etc. ut these changes were insignificant compared to the changes that the brand underwent…...
mlaBibliography:
Gobe, Marc. Emotional branding, the new paradigm for connecting brands to people. Allworth press. 2001
Kluger, Richard. Ashes to Ashes: America's Hundred-Year Cigarette War, the Public Health, and the Unabashed Triumph of Philip Morris. New York: Alfred A. Knopf, 1996.
Pricken, Mario. Creative advertising. Thames & Hudson. 2008.
Ogilvy, David. Ogilvy on advertising. Vintage, 1985
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