Verified Document

Thyroid Hormone In Carcinoma Thyroid Hormones The Research Paper

Thyroid Hormone in Carcinoma Thyroid Hormones

The author of this report is asked to review an article and the topic chosen from the acceptable list of topics regards the role and involvement of thyroid hormones in certain disorders. The particular article reviewed for this report focused on the activation of tumor cell proliferation by secretions from the thyroid gland in mice. The specific cancer involved was follicular thyroid carcinoma. Per the requirement of the assignment, the article in question is less than two to three years old. Indeed, it was published last year.

The article starts off by noting that thyroid cancer variants are by far the most common malignancy of the endocrine system in humans. The article notes that the main goal of the research behind the report had the goal of the parallels and similar causes of follicular thyroid carcinoma and thyroid carcinogenesis...

To prove their point, they completed neutered thyroid production in some mice. The article notes that cell proliferation and apoptosis are two major processes that affect tumor growth in people with thyroid-related cancers (Lu, Zhu, Willingham & Cheng, 2012).
The study found, and stated in the discussion section, that the altered mice mentioned in the prior paragraph follow the same patterns and results found in humans with similar thyroid issues. The study's discussion notes that the use of mice allows them to toy and experiment in an environment that does not affect humans as they are not the study subjects in this study, and ones like it, but it is still possible to draw conclusions and findings that can likely (if not certainly) be parlayed to research on similar results, outcomes and treatment methods in humans. This is not usually the case and monkeys and other animals…

Sources used in this document:
References

Lu, C., Zhu, X., Willingham, M., & Cheng, S. (2012). Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma. Oncogene,

31(16), 2007-2016. doi:10.1038/onc.2011.390
Cite this Document:
Copy Bibliography Citation

Related Documents

Turner Syndrome Date, Month and
Words: 2711 Length: 7 Document Type: Term Paper

Particularly, the risks of diverse neoplasms have been seen to be raised in Turner Syndrome is quite low quantum, however, except for gut cancer and gonaboblastoma in patients having occult Y chromosome sequences. (Cabanas; Garcia-Caballero; Barreiro; Castro-Feijoo; Gallego; Arevalo; Canete; Pombo, 2005) Additionally, there appear to have no prior indication of the relationship between the Turner Syndrome and papillary thyroid carcinoma, irrespective of the fact that there has been one

68 GA Dota TOC Radiopharmaceutical
Words: 1828 Length: 6 Document Type: Research Proposal

Ga DOTA TOC Radio Pharmaceutical Neuroendocrine tumors (NET) are neoplasms characterized by tissue immunoreactivity for neuroendocrine differentiation markers, appearance as a small mass that can be off white to yellow often in submucosa and prevalence throughout the body but typically found in the intestine or lungs (Oberg2011). The tumors can be malignant and are typically detected through hormone markers in a first diagnosis (Arnold 2003). Because of the diffuse nature of

Amidation of Peptides
Words: 6068 Length: 20 Document Type: Term Paper

Amidation of Peptides in Humans Modern biotechnology has experienced dramatic leaps in the body of knowledge concerning molecular processes in peptides and how they work. Many of these processes rely on amidation of peptides to achieve increasingly important medical and commercial applications. Peptides are created when two or more amino acids are covalently joined by peptide bonds, a process termed post-translational modification. One increasingly valuable application of post-translational modification is

Sign Up for Unlimited Study Help

Our semester plans gives you unlimited, unrestricted access to our entire library of resources —writing tools, guides, example essays, tutorials, class notes, and more.

Get Started Now