Ian Wimut and Keith Campbell could effectively clone two sheeps named Megan and Morag in July 1995 from the differentiated embryo cells. (History of Cloning)
Dolly originated on July 5, 1996 as the first organism ever to be cloned from adult cells. Following the announcements for creation of Dolly by Ian Wilmut, an extensive debate on human cloning ethics emerged and that led President Clinton to propose for a five-year moratorium on federal as well as privately invested human cloning research on March 4, 1997. Richard Seed, a Havard graduate could announce on December 5, 1997 about his objective of cloning a human being prior to ban of the process by enactment of the federal laws. Following the successful cloning of Dolly, Ian Wilmut and Keith Campbell generated Polly, after cloning of a Poll Dorset lamb from skill cells grown on a lab and with its alteration genetically to incorporate a human gene, in July 1997. Ryuzo Yanagimachi, Toni Perry, and Teruhiko Wakayama of the University of Hawaii claimed in July 1998 that they had cloned fifty mice from adult cells since October 1997. (History of Cloning)
The different types of cloning and how they work - an overview:
Only one case of cloning that is reproductive cloning was taken into consideration by the media while reporting on it. However, there existed several types of cloning and the technologies of cloning can effectively be applied for other purposes than simply generating genetic twin of another organism. The awareness of various kinds of cloning is considered fundamental to have an informed attitude on the present public policy concerns and to advance the best possible personal conclusions. Three kinds of cloning technology are generally debated such as Recombinant DNA technology or DNA cloning, Reproductive cloning and Therapeutic cloning. The Recombinant DNA technology or DNA cloning indicates the process where the transfer of a specific DNA fragment from one organism to a self-replicating genetic element like bacterial plasmid is generated. The specified DNA can then be conveniently proliferated in a foreign host cell. This technology is in operation ever since 1970s and it has become the common experience in molecular biology labs presently. (Cloning Fact Sheet)
The Reproductive Cloning is a tool applied to create an animal having similar nuclear DNA like that of another previously or presently existing animal. Dolly was generated with the application of reproductive cloning technology. The scientists attempt to transfer genetic material from the nucleus of a donor adult cell to an egg where the nucleus and thus the genetic material is removed by means of a process known as 'somatic cell nuclear transfer'-SCNT. The reconstituted egg consisting of DNA from a donor cell is required to be treated with chemicals or electric current in order to stimulate cells division. The cloned embryo is transferred to the uterus of a female host once the cloned embryo attains an appropriate stage in its process of development and continues to grow until birth.
The Therapeutic cloning also known as the 'embryo cloning' is considered generation of the human embryos for its application in research. The objective of this process is not to generate the cloned human beings, but to harvest stem cells that can be applied to study human development and to treat disease. The stem cells are considered significant in the field of biomedical researchers since they are conveniently applied to produce any sort of specialized cells in the human body. Stem cells are extracted from the eggs after its division for 5 days. The egg at this stage of development is known as a blastocyst. The ethical concern arises out of the fact of destruction of the embryo in the extraction process. (Cloning Fact Sheet)
2. Legal Section
The lawmakers all over the country are struggling to find out the structure of laws on cloning both at the federal and state levels. Most of the law-makers perceive therapeutic cloning as infusing optimism among the millions of Americans with sufferings of debilitating diseases are they are to be encouraged and even funded by the government. According to some others cloning irrespective of its uses- reproductive or therapeutic is to be condemned in its entirety. (Cloning: what's stopping us? Law) Human cloning has been banned by state laws in seven states presently. These states are: California, Iowa, Louisiana, Michigan, Missouri, Rhode Island, and Virginia. However, the laws implemented differ widely in its scope with some banning only state funding of human cloning research and others banning...
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