And Li, (2006). These researchers took previous findings regarding the efficacy of ACE inhibitors (Fosinopril, in particular) and applied them to children of different racial populations. Moreover, Menon et al. (2006) investigated whether the evidenced differences in effectiveness of ACE inhibitors among adults of different racial groups transferred to children of different racial groups. The results of the study indicated that Fosinopril was effective in treating hypertension in all racial groups, but Black children in the study required a higher dosage of the anti-hypertensive medication in order to experience the beneficial results. Furthermore, the differences in ACE inhibitor efficacy observed among adults of different races exist also in children of various races (Menon et al., 2006).
The demonstrated fact that African-Americans with hypertension are not as responsive to certain anti-hypertensive medications than non-African-Americans has opened the door for further research. Papademetriou, Narayan, and Kokkinos (2004) studied the effectiveness of ACE inhibitors in relation to angiotensin receptor blockers and the extent of cross-resistance to these anti-hypertensive agents among African-Americans. Results indicated that approximately equal proportions of the population under study responded favorably to each type of medication, while only a small proportion (14%) responded to both types of medication and a rather large proportion (48%) were non-responsive to either medication (Papademetriou et al., 2004).
Other factors to examine regarding the effectiveness of anti-hypertensive medications among ethnic groups are differences in adverse reactions to these agents. McDowell, Coleman, and Ferner (2006) systematically reviewed evidence for differences among ethnic groups in regards to susceptibility to adverse drug reactions as a result of the administration of cardiovascular drugs. The results of the study concluded that patients from various ethnic groups exhibit different risks for adverse drug reactions in response to cardiovascular medications. For instance, the relative risk of angio-oedema resulting from...
Prescription, Nonprescription and Herbal Medicines Prescription, Non-prescription and Herbal Medications: Exploring Interactions in the Geriatric Population Geriatric medicine, generally referred to as just "geriatrics" is a branch of internal medicine and health care that focuses primarily on the diagnoses, prevention, care and treatment of disease and disability in elderly patients. Elderly patients involve those senior members of the population that develop a disability, or are suffering from a disease that is a
Introduction Health disparities refer to avoidable dissimilarities existing in the occurrence of violence, disease and injury or in the opportunities for enjoying peak health which is faced by minority and social disadvantaged ethnic and racial populations and communities. Health differences are present across every age group, even in the older adults. Even though general health and life expectancy have both gotten better of recent, the Centres for Disease Control and Prevention
Hypertension is defined as systolic BP of at least 140 mm HG and diastolic BP of at least 90 mm Hg, self-reported use of antihypertensive medications, or both. (Ostchega, 2005-2006) Hypertension, according to the joint national committee 6 and 7, is classified into the following stages: Classification of Blood Pressure for Adults Aged ? 18 Years: JNC 7 versus JNC JNC 7 Blood Pressure Category JNC 6 Blood Pressure Category SBP (mm Hg) and/or DBP (mm Hg) Normal Optimal < 120 Pre-hypertension Or Normal < 130 High-normal Or Hypertension: Hypertension: Stage Stage Or Stage Or Stage Or Stage Or (Linda
Treatments BEST TREATMENTS Constipation, Hypertension, Seizure Constipation This is the infrequent or difficult bowel evacuation (Mayo Clinic Staff, 2012). While there are no strict standard for bowel elimination, it is generally believed that fewer than thrice a week constitutes constipation. Stools are usually hard and dry. Other common symptoms associated constipation include excessive straining during bowel evacuation, a sense of rectal blockage, a sense of incomplete evacuation and the need to perform manual measures
Pharmaceutical industries have to operate in an environment that is highly competitive and subject to a wide variety of internal and external constraints. In recent times, there has been an increasing trend to reduce the cost of operation while competing with other companies that manufacture products that treat similar afflictions and ailments. The complexities in drug research and development and regulations have created an industry that is subject to intense
In the third trimester of pregnancy, caution must be taken concerning congestive heart failure, hypertension and decreased renal and hepatic function, interstitial nephritis, hyperkalemia, hyponatremia and renal papillary necrosis, anticoagulation abnormalities, leucopenia, granulocytopenia and thrombocytopenia. The use of Celecoxib is aimed primarily at suppressing pain and inflammatory stimuli, but it may contribute to NSAID gastrointestinal toxicity. The lowest possible dose of celecoxib should be prescribed and taken. On the
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