Lipitor is a brand name of Atorvastatin, one of the most commonly prescribed medications in the United States. Atorvastatin belongs to the statin family of drugs, which react with specific enzymes in order to lower cholesterol in the body. Lipitor/atorvastatin inhibits HMG-CoA reductase, an enzyme that "converts 3-hydroxy-3methylglutaryl-coenzyme A to mevalonate, a precursor of sterols" like cholesterol ("Lipior," n.d.).
Elevated plasma levels of total cholesterol (both LDL-cholesterol or LDL-C and HDL) as well as levels of apolipoprotein B (apo B) are known precursors or risk factors in human atherosclerosis and are risk factors for developing cardiovascular disease. By reducing the amount of cholesterol in plasma as well as in the liver, the drug helps to prevent atherosclerosis and cardiovascular disease. Lipitor is effective in addressing elevated cholesterol due to hereditary hypercholesterolemia, as well as nonfamilial types. Lipitor is indicated for patients with increased risk of myocardial infarction, stroke, and angina.
The drug is primarily active in the liver, which is the primary site of cholesterol synthesis ("Lipitor," n.d.). After metabolism in the liver, Lipitor and its metabolites are eliminated in bile. Very little of the drug is eliminated in urine. The "mean plasma elimination half-life of Lipitor in humans...
Interactions: the patient had informed me about his medical history and his psychological state so as to compensate and recommend the best possible drug dosage. Nursing implications: This drug has mild side effects. However, the patient was still advised to consult me if any unusual problems occurred. Client Implications: the eye irritation caused by swimming had been completely cured. Patient Education: the patient had been instructed to ensure regularity in all his appointments 9.
Pharmacology: Moclobemide Moclobemide is classified as an antidepressant, a MAO (monoamine oxidase) inhibitor. Antidepressants are designed to inhibit the reuptake or reabsorbtion of specific neurotransmitters, increasing the levels of these neurotransmitters around the nerves of the brain (Gbemudu, 2011:1). Neurotransmitters such as serotonin, dopamine and norepinephrine (noradrenaline) are often called 'feel good' chemicals that elevate the patient's mood. Drug class A deficit of mood-enhancing chemicals is associated with depression, although there is no
Pharmacology DVT: In the legs, there are two kinds of veins, namely, deep and superficial. The deep veins pass through the middle of the leg, enclosed by the muscles. A blood clot or thrombus that crops up in the deep veins of the leg is called a Deep Vein Thrombosis or DVT. Blood clot, and hence DVT, can arise due to slowing down or stoppage of blood or due to damage of
Pharmacology of Beta Lactam Antibiotics Beta Lactam Antibiotics This class of antibiotic agents, including penicillin derivatives, (penams), cephalosporins (cephems), monobactams, and carbapenems, is the most widely used antibiotic. In fact, more than half of the antibiotics that were commercially sold in 2003 were ?-lactam compounds. Beta lactam antibiotics are characterized by a molecular ?-lactam ring structure (Drawz & Bonomo, 2010). The beta lactam antibiotics inhibit the biosynthesis of the cell walls of
Nevertheless, an unscheduled PT test performed in the ER during her second visit provided markedly different results indicating a prolonged coagulation time despite no known changes to the patient's medication regimen or diet. As a result of the results of the PT test performed in the ER, her physician lowered her daily dosage of Coumadin to 2 milligrams per day, with instructions to repeat PT testing weekly for the time
Pharmacology is the study of drugs and their effects on living organisms. It is a vast and complex field that encompasses a wide range of topics, including drug discovery, development, and clinical use. Nurses play a vital role in pharmacology, as they are responsible for administering and monitoring medications, as well as educating patients about their medications (Karch, 2021). Nurses must have a thorough understanding of pharmacology in order to safely
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