Nursing - Asthma
The limitation of airflow in asthma is reported as "recurrent and caused by a variety of changes in the airway." (Expert Panel Report 3, National Heart, Lung, and Blood Institute, 2007, p.1) Those changes include: (1) bronchoconstriction; (2) airway edema; (3) airway hyperresponsiveness; and (4) airway remodeling. Expert Panel Report 3, National Heart, Lung, and Blood Institute, 2007, p.1) Airway edema occurs with the progression of the disease and the inflammation is more progressive and exacerbated by "edema, inflammation, mucus hypersecretion and the formation of inspissated mucus plugs as well as structural changes including hypertrophy and hyperplasia of the airway smooth muscle." (Expert Panel Report 3, National Heart, Lung, and Blood Institute, 2007, p.1) Airway hyperresponsivenss is reported to be "an exaggerated bronchoconstrictor response to a wide variety of stimuli. Airway modeling speaks of the permanent structural changes in the airway reported to be associated with "loss of lung function that is not prevented by or fully reversible by the current therapy." (Expert Panel Report 3, National Heart, Lung, and Blood Institute, 2007, p.1)
Pathophysiology of Chronic Asthma
Factors that limit airway flow...
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