There are two tumors that are often mistaken for GISTs and specifically those known as: (1) Fibromatosis; and (2) leomysarcoma. (Rubic, Heinrich, and Corless, 2007)
Findings in this study include that there apparently are genetic bases for development of gastrointestinal stromal tumor and that in the Chinese population that when comparing the U.S. And Hong Kong demonstrates that Hong Kong is comparable to the U.S. And lower than Finland. This is likely to be true for the entire Chinese population although this fact could not be confirmed in the present study. Findings in this study additional include the findings that the previous optimal treatment for GISTs is likely not to be the best method of treating this condition and indicating that further and additional research is required toward the necessity and needs of different treatment options that are evidence-based and found to be more effective in treating this condition.
Bibliography
Azhar, a.H.S., et al. (2009) a Retrospective Cohort Study of Gastrointestinal Stromal Tumours (Gist) in Husm for the Last 12 Years (1997 -- 2008) Department of Surgery, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. Online available at: http://www.colorectalmy.org/events/coloproctology_2009.pdf
Chan K, Chan C, Chow W, Kwan W, Kong C, Mak K, Leung M, Lau L.Gastrointestinal stromal tumors in a cohort of Chinese patients in Hong Kong.World J. Kastroenterol 2006 April;12(14):2223-2228
Corless, CL; Fletcher, JA, and Heinrich, MC (2004) Biology of gastrointestinal stromal tumors. Clin Oncol. 2004 Sep 15;22(18):3813-25.
Demetri GD, von Mehren M, Blanke CD, et al.: Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J. Med 347:472-480, 2002.
Heinrich MC, Corless CL, Duensing a, et al.: PDGFRA activating mutations in...
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