Verified Document

Human Gene Therapy - The Term Paper

Strand that pair specifically with the intron next to the mutated segment of mRNA and leaves the correct strand. b. Simultaneous delivery of a correct version of the segment to replace the mutated piece in the final RNA product.

Translation of the repaired mRNA to produce the normal functional protein.

Triple Helix-Forming Oligonucleotide: Oligonucleotides that bind the double strand of the mutated gene's DNA and actually forms a triple strand that blocks the mutation.

Antisense Technology is used to turn off a mutated gene in a cell by targeting the mRNA transcripts copied from the gene according to Crabtree. Further discussed in the role of Ribozymes (RNA enzymes). It is possible to have delivery of RNA strand that has been engineered to function as ribozymes to the cell, the RNA is encoded by a mutated gene preventing...

Small interfering RNA (SIRNA) finds and attaches to the mRNA taking advantage of the natural pathway with natural cellular processes and gene specific inhibition of expression.
Kay Crabtree voiced the information in a clear and concise manner and presented the information in an understandable and comprehensible format.

Clinical Trials: presented by Melissa Fladseth

Methods of delivery in gene therapy are "Exvivo" or outside of the patient, "Gene Transfer" and "Viral Vectors." Before a clinical trial with human involvement the plans are reviewed by physicians as well as the Internal Ethics and Safety Review Board (IRB) and the Recombinant DNA Advisory Committee of NIH (RAC). The Food and Drug Administration (FDA) is also involved in the testing and approval. Phase One is the assessment

Cite this Document:
Copy Bibliography Citation

Related Documents

Psychology How Animal Therapy Assists Various Kinds
Words: 928 Length: 3 Document Type: Essay

Psychology How Animal Therapy Assists Various Kinds of Patients Animals and humans have had a long and multifaceted relationship over time. There are many of us who have visited petting zoos, regular zoos, and kept pets in our homes. People who have bonded with animals know first hand how strong the connection can be between a person and an animal. It is only been in the past several decades where formal research

Drug Therapy Vs Animal Therapy
Words: 2031 Length: 7 Document Type: Research Paper

Poor Children, the Problem of Drug Therapy and Possible Alternatives Introduction Foster children are more likely than children in the general population to have mental health issues (Polihronakis, 2008). Part of the reason for this is that foster children are in foster care because they have been neglected in their own homes, their parents are incapable of providing food, love, shelter and nourishment, and they are in need of a nurturing environment.

Carl Rogers the Ideal Self and Animal Therapy
Words: 1743 Length: 6 Document Type: Evidence Based Practice

Evidence-Based Programs and Practices Part 1: Define and Refine Evidence-Based Theories Evidence-based programs are defined as a prevention or treatment practice, that is based on consistent scientific evidence providing proof that the practice improves client/patient outcomes. The practice should be supported by sufficient documentation and peer-reviewed research that shows its effectiveness (Operational Definition for Evidence-Based Practices Addictions and Mental Health Division, 2017). Programs draw from theory in that the theoretical framework developed by researchers

Animal Assisted Therapy Animals When
Words: 2537 Length: 7 Document Type: Term Paper

69). Petting a dog lowered blood pressure and respiratory rate -- even if the dog was somebody else's. Pet owners that have heart surgery recover faster and stand a better chance of full recovery. Touching a warm furry animal gives them relief. Moreover, pet ownership is a predictor of survival after hospitalization for any serious illness (Gunter & Furnham, 1999). Demello (1999) found that the "mere presence of an animal" could

Animal Testing for Products Animal
Words: 1456 Length: 4 Document Type: Term Paper

Animal testing is not only for the benefit of the humans but is also beneficial to the animals themselves. "The research of the National Institute of Environmental Health Sciences benefits animals because NIEHS research contributes to protecting the environment for all the life that shares the earth - companion animals, farm animals, wildlife, marine life - and plant life as well" (Anonymous). Much more animals are consumed as a

Animal Rights and Experimentation Animal Rights Are
Words: 2142 Length: 7 Document Type: Term Paper

Animal Rights and Experimentation Animal rights are being constantly violated in this day and age. They are being subjected to endless experimentation in order to ensure a healthy life for humans. This is known as vivisection. The local industries use tests, which kill around 50% of the animals during the tests. It is sad to know that tests are still being conducted on animals in spite of having results. Experts have

Sign Up for Unlimited Study Help

Our semester plans gives you unlimited, unrestricted access to our entire library of resources —writing tools, guides, example essays, tutorials, class notes, and more.

Get Started Now