Lamivudine (100 mg) - monthly cost $204- annual cost $2,482

Adefovir (10 mg) - monthly cost $546 - annual cost $6,647

Entecavir (0.5 mg) - monthly cost $715 - annual cost $8,694

Peginterferon alfa-2a (180 mcg) - monthly cost -$1,540 - annual cost $18,480

Emtricitabine (200 mg) - monthly cost $318 - annual cost $3,872

Tenofovir (300 mg) - monthly cost $478 - annual cost $5,811

( Hepatitis B Foundation, B Informed Newsletter, No. 46, Summer 2006)

References

Approved Drugs for Adults. July 17, 2009.

Kanwal et al. Treatment Alternatives for Chronic Hepatitis B Virus Infection: A Cost-

Effectiveness Analysis. Annals of Internal Medicine. Vol. 142, 10. July 17, 2009.

Hepatitis. July 17, 2009.

Hepatitis B July 17, 2009.

Hepatitis B: Brown.Edu. July 17, 2009.

Hepatitis B Foundation, B Informed Newsletter, No. 46, Summer 2006. July 17,

2009.

Hepatitis B Overview. July 17, 2009.

Hepatitis B Symptoms. July 17, 2009.

Appendix

1. Approved Hepatitis B Drugs in the United States

Interferon Alpha (Intron A) is given by injection several times a week for six months to a year, or sometimes longer. The drug can cause side effects such as flu-like...

Approved 1991 and available for both children and adults.
Pegylated Interferon (Pegasys) is given by injection once a week usually for six months to a year. The drug can cause side effects such as flu-like symptoms and depression. Approved May 2005 and available only for adults.

Lamivudine (Epivir-HBV, Zeffix, or Heptodin) is a pill that is taken once a day, with few side effects, for at least one year or longer. Approved 1998 and available for both children and adults.

Adefovir Dipivoxil (Hepsera) is a pill taken once a day, with few side effects, for at least one year or longer. Approved September 2002 for adults. Pediatric clinical trials are in progress.

Entecavir (Baraclude) is a pill taken once a day, with few side effects, for at least one year or longer. Approved April 2005 for adults. Pediatric clinical trials are in progress.

Telbivudine (Tyzeka, Sebivo) is a pill taken once a day, with few side effects, for at least one year or longer. Approved October 2006 for adults.

Tenofovir (Viread) is a pill taken once a day, with few side effects, for at least one year or longer. Approved August 2008 for adults.

( Source: Approved Drugs for Adults )

See Appendix for a list of the most commonly used drugs