The exchange of the defective gene could be brought about by a process called homologous recombination. One of the first gene therapy experiments, though well intentioned, caused the death of the patient. Researchers at the University of Pennsylvania introduced a normal gene into a boy's body by using the rhino virus as a carrier. The body's immune system attacked this as a pathogen. This led to eventual organ failure and death. Gene therapy projects all over the world were largely abandoned. But more recently, gene therapy is beginning to make a comeback. (ORNL, 2009)
Gene therapy has been tested in the treatment of Alzheimer's disease. This is not a treatment that targets amyloid beta proteins or the tangles, but protects the brain cells from destruction. The regenerative properties of skin cells (stem cells) have been used to prevent the brain cells from "withering" away. Positron Emission Tomography (PET) scans reveal greater brain activity because it reduces the cell death. The improvement rates are up to 50%, which gives hope to the researchers.
Researcher Gary Small and his team have attempted to work on methodologies to prevent the cause of Alzheimer's disease. This involves scanning people within a certain age groups. The scans are designed to reveal both the over expression of amyloid-beta proteins as well the existence of neurofibrillary tangles. These scans will be useful in identifying patients who are susceptible to Alzheimer's disease. (Elements4health, 2009)
One of the common features of this article is that large scale later phase human trials have not been run on any of the treatment modalities. It can be concluded therefore that these treatments have potential but have not yet been proven. Indeed, most local news on television has a health segment, where possible therapies for common ailments are touted. But there is no follow up about whether the research has borne fruits. The Pharma lobby was instrumental in getting Congress to allow the advertisement of pharmaceutical products on television. All advertisements follow a similar pattern. After the description of how this product can cure a disease, the advertisement suggests that the viewer should ask the doctor about a certain treatment. The advertisement, to protect the company from lawsuits, also lists all the possible side effects from taking the product. Anne Underwood, much like other mass media outlets, creates an impression that a treatment for Alzheimer's is imminent. Underwood sets...
At functioning temperatures higher than 1000°C, the most imperative heat-transfer instrument becomes emission instead of conduction and convection, which are the more noteworthy heat-transfer devices at lower temperatures. The outsized pores in the cement IFB are wasteful at decreasing energy reassignment at the infrared wavelengths concerned, so this kind of IFB shows a superior thermal conductivity in comparison with the cast. On the other hand, the microporous arrangement of the
Apple Corporation SWOT analysis Apple Inc. is one of the well-known and recognized enterprises by not only the business community but populace from all over the world are cognizant about this corporation. It started off its business from the decade of 1970 that has been involved in the designing, manufacturing and offering its consumers with a wide range of innovative and technologically refined products like computers, software, music players and its
Japanese-American Biopharmaceutical Industry in the 21st Century Optimizing Ethical Drug Availability Between These Two Pharmaceutical Superpowers" The Japanese-American biopharmaceutical industry represents an ongoing international effort between the two top pharmaceutical markets in the world. These two economic powers provide consumers with a majority share of all pharmaceuticals produced in the world. However, a number of pharmaceutical products that are currently available to U.S. residents are unavailable to Japanese consumers. From a humanitarian perspective, this
2015 will be the year of innovation for UAE which will involve the Traditional methods of innovation system analysis that will mostly put the focus on describing the structure of an innovation system. This is being done because in the past it has been argued that it has proved to be inadequate for understanding the factors and procedures that drive and bear innovation (Kan, 2015). In many studies, the
Effect of External and Internal Environment Introduction Organizations have both an internal and external environment. To begin with, the forces or circumstances within the borderline of the organization are the components of the internal environment. Notably, the internal environment comprises for the most part of the owners, employees, board of directors, stakeholders, and the corporate culture. On the other hand, factors that are extrinsic to the organization are the components of the
Governments in these developing countries also may have issues with foreign companies expanding within their borders. Lastly, establishing local suppliers, and the infrastructure required for these suppliers, may be a challenge, especially for those they develop from the ground up. Strategic Posture: Nestle's mission statement is simple. "Good Food, Good Life'. That mission is to provide consumers with the best tasting, most nutritious choices in a wide range of food and beverage
Our semester plans gives you unlimited, unrestricted access to our entire library of resources —writing tools, guides, example essays, tutorials, class notes, and more.
Get Started Now