¶ … gene therapy. The writer looks at its history, its use and the possible problems it presents. There were four sources used to complete this paper.
Medical science has done amazing things in recent years. Through the use of research the average lifespan is longer than ever before, and the quality of life continues to rise. Recently it seems there is nothing medical science cannot make happen. Today the world stands at the edge of some of the most exciting technology than it ever dreamed possible. Gene therapy is a reality and the world currently debates whether or not it wants to take the leap. There are some who are excited and believe it will save lives and provide cures for things that used to mean long suffering death, while others fear it is going to open the world to clones and untested waters. The religious sectors believe gene therapy is playing God and that is not something they are willing to dabble in. Gene therapy is a promising new venture in the medical world, but one that must be tempered with common sense as well as logic if it is to become the success it is capable of being.
THE PLUS SIDE
There are many positive aspects to the recently developed science called gene therapy. The manipulation of genes promises to allow the curing of diseases, as well as the growing of organs. It could mean the end of thousands people dying each year waiting for organs that never come. It could mean children no longer suffering, becoming more and more crippled with time and dying before ever reaching adulthood. It could mean many positive things. There had been some disappointment in the area of cures as research failed to replicate earlier studies, but a recent break though ion France cured four "bubble boys" of their life threatening conditions, which re-sparked the race to explore the science completely. Several companies...
Gene Therapy The treatment of genetic diseases has appeared a daunting challenge because there seemed little to be done if the immutable basic blueprints of the body have a serious imperfection (Beutler Pp). Even fifty years ago it was possible to greatly improve the quality of life and to actually "save the lives of patients with some such genetic diseases" (Beutler Pp). Success approaches included dietary manipulation as in phenylketonuria or
When these cells behave in an abnormal manner, it can lead to acute myeloid leukemia. Various gene therapy-based tests have been conducted on the guinea pigs as model animals. The gene therapy-based experiments have shown that deafness can be cured with the help of gene therapy. One of the main reasons of the deafness is the destruction of hair cells in the cochlea. A gene that has been known
Gene Therapy FDA Ethics can be considered to come from personal values. From both a medical and a business perspective, ethics are the reasons that some news stories should be followed from beginning to end and all in between. "On Sunday morning, 23 February 1997, the world awoke to a technological advance that shook the foundations of biology and philosophy. On that day, we were introduced to Dolly, a 6-month-old lamb that
Implications for ongoing research into genetic therapies and side effects/later developments are discussed at length. Yannaki, E. & Stamatoyannopoulos, G. (2010). Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease. Annals of the New York Academy of Sciences 1202: 59-63. Though the clinical trial these two researchers are involved in does not yet have results that are ready for publication, the review of the risks
In the case of Jesse Gelsinger it was found out later that there were many rules and regulations that were in place not followed to the letter of the law like they should have been. When peoples lives are at stake it is imperative that not only are their strict rules and regulations set down but that there is a process in place to make sure that those involved
Of this there are two types: Splicsome mediated - the delivery of RNA (a Repair Method) a. Strand that pair specifically with the intron next to the mutated segment of mRNA and leaves the correct strand. b. Simultaneous delivery of a correct version of the segment to replace the mutated piece in the final RNA product. Translation of the repaired mRNA to produce the normal functional protein. Triple Helix-Forming Oligonucleotide: Oligonucleotides that bind
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