This is stated in current research to have been shown that the 'extra gene dosage caused by the abnormal third chromosome of Down syndrome might be a factor in the development of Alzheimer's disease. Interest also is being focused on the early onset of Alzheimer's disease in individuals with Down syndrome, which might be related to the early aging of the Down syndrome brain." (Cleveland Clinic, 2009)
Summary and Conclusion
This review is not meant to be all encompassing of the knowledge existing concerning Down syndrome and it must be stated that the ranges of effects and symptoms as well as the medical conditions accompanying this syndrome are very diverse in nature. As more knowledge is gained in the study of Down syndrome, it is likely that the present good prognosis for those with Down syndrome will become an even better prognosis both in terms of individual longevity and quality of life for the individual with Down syndrome.
Bibliography
Down Syndrome (2009) Mayo Clinic -- Mayo Clinic Staff. Online available at: http://www.mayoclinic.com/health/down-syndrome/DS00182/TAB=indepth
Down Syndrome and Alzheimer's Disease (2009) Cleveland Clinic. Online available at: http://my.clevelandclinic.org/disorders/alzheimers_disease/hic_alzheimers_disease_and_down_syndrome.aspx
Shapiro BL. Down syndrome and associated congenital malformations. J Neural Transm Suppl. 2003;(67):207-14. Review
Shapiro, Joseph (2009) Down Syndrome Births Rise Unexpectedly. NPR 1 Dec 2009. Online available at: http://www.npr.org/blogs/health/2009/12/down_syndrome_births_rise_unex.html
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Et al. "Psychological Responses of Women After First-Trimester Abortion." Arch Gen Psychiatry. Volume 57.8 (2000): 777-84. Lexis Nexis Rearden, David C. "Abortion and Subsequent Substance Abuse." The Journal of Drug and Alcohol Abuse. Vol 26.1 (2000): 61-75. Wiley Online Library Rosen, Gerald; Spitzer, Robert; McHugh, Paul. "Problems with the post-traumatic stress disorder diagnosis and its future in DSM-V." British Journal of Psychology. Volume 192 (2008): 3-4. Hard Copy Speckhard, Anne; Rue, Vincent.
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