For a research paper on the significance of the pharmaceutical industry and the business aspects of that, you could consider:
* Strategic management of the pharmaceutical companies.
* The overall business model for pharmaceutical companies.
* Problems that are facing the business aspect of the industry.
* How changing laws are affecting the pharmaceutical business.
There are others, of course, and you can also narrow down one of the options here to provide something more specific. Maybe pick a particular pharmaceutical company and do an analysis on how the health care law may affect it? Finding a topic that's narrow enough is key, so you can stay focused when writing your paper.
