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Treatment Of Asperger Syndrome Research Paper

Treatment of Asperger Syndrome Asperger syndrome is considered an autism spectrum disorder that is characterized by impairments in social interaction and communication, as well as repetitive and restricted patterns of behaviors and interests, which manifest to a degree where the individuals with this disorder are still "high-functioning," and more able in the realms of various intelligences in comparison to those with autism (Toth & King, 2008). This disorder has been found to occur at a rate of 2.5 in every 10,000, while all autistic disorders occur at a rate of 60 in every 10,000 (Toth & King, 2008). There is a strong hereditary component to Asperger syndrome, as a study investigating family histories of one hundred males with Asperger syndrome determined that there was a history of autistic spectrum disorder in 50% of the sample, as well as pre-natal and peri-natal risk factors, including alcohol exposure, neonatal seizures, premature birth, and postnatal asphyxia, in one quarter of the sample (Toth & King, 2008). Asperger syndrome is sometimes used as a diagnosis for children with autism that do not present typical symptomatology and who instead of being distant or avoidant, often initiate social interactions (Toth & King, 2008). The criteria for a diagnosis of Asperger syndrome according to the DSM-IV-TR include cognitive ability that is intact as well as the absence of any early language delays.

Causes of Asperger syndrome include fetal abnormalities, as well as genetic and environmental factors (Toth & King, 2008). As far as genetic factors are concerned,...

Research on individuals with Asperger syndrome has identified two loci on chromosomes 1 and 3 that are likely involved in the genetics surrounding autistic disorders, further pointing to Asperger Syndrome as a less severe form of autistic disorder rather than a completely separate disorder (Toth & King, 2008).
The neurobiological correlates of Asperger syndrome are not well understood, and further research is required in this area (McAlonan et al., 2002). However, there are certain characteristics of Asperger syndrome that point to specific biological factors involved in the manifestation and expression of the disorder. For example, individuals with Asperger syndrome commonly demonstrate a lack of interest in the human face, preferring inanimate objects instead (Schultz et al., in press). This characteristic results in negative effects with regard to developing healthy and successful interpersonal relationships (Schultz et al., in press). Anatomically, this lack of interest in faces may be associated with abnormalities in the activation in right inferior temporal gyri (Schultz et al., in press).

In particular, face recognition among individuals with Asperger syndrome and autism yielded increases in the activity in the right inferior temporal gyri and reduced right fusiform gyrus…

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McAlonan, G.M., Daly, E., Kumari, V., Critchley, H.D., van Amelsvoort, T., Suckling, J., Simmons, A., Sigmundson, T., Greenwood, K., Russell, A., Schmitz, N., Happe, F., Howlin, P., Murphy, D.G.M. (2002). Brain anatomy and sensorimotor gating in Asperger's syndrome. Brain, 127, 1594-1606.

Schultz, R.T., Gauthier, I., Klin, A., Fulbright, R.K., Anderson, A.W., Volkmar, F., Skudlarski, P., Lacadie, C., Cohen, D.J., Gore, J.C. (In Press). Abnormal ventral temporal cortical activity among individuals with autism and Asperger syndrome during face discrimination. Archives of General Psychiatry.

Toth, K. & King, B.H. (2008). Asperger's syndrome: diagnosis and treatment. American Journal of Psychiatry, 165(8), 958-63.
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