Alzheimer's Disease: Summary of Results Q&A
The summary of results on the case study of AD provides that AD is still a disease of those primarily age 85 and older, and an expensive, time-consuming process. It is not a disease that is appropriate for "large, epidemiologic studies" thus screening strategies are most sell-suited so cohort studies are feasible. Diagnostic workups assist in making studies manageable and successful in diagnosing sources of AD and number of actual cases of AD in the public.
Diagnosis of AD brings with it many problems including fear and social stigma; thus it is beneficial to examine risk factors and distinguish between cognitive impairments that are minimal and evidenced in the public at large and actual early warning signs and preclinical AD. False positives are a common diagnostic problem as signs are common with advancing age and may include, "poor vision, hearing loss, arthritis" which all affect performance on examination which include mental status examination and neuropsychological examination, as do environmental factors which may contribute to examination errors. False positives may be eliminated with careful cross-sectional analysis or observational studies that take into consideration the unique characteristics of the population at large.
1.Do you agree or disagree with answer Case Study 1 -- Why?
An observational study to examine the association between AD and smoking is the best choice given the information provided in the summary, as there are too many influencing factors (environmental, advancing age, altered mental status) that can affect the results leading to a diagnosis...
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