Discussion
Sodium and potassium could be seen as the dynamic duo critical for normal functioning of several processes in the body. In addition to assessing the role the sodium-potassium pump plays in the propagation of an action potential, this text will also highlight both the pathophysiologic impact of hyperkalemia on the action potential as well as the resulting clinical manifestations.
The Role of the Sodium-Potassium Pump on the Propagation of an Action Potential
In essence, messages sent by axons, according to Kalat (2012), are referred to as action potentials. In the context of this discussion, therefore, action potential has got to do with the electrical potential changes as a consequence of impulse passage along a nerve cell’s membrane.
The generation of action potential is dependent upon active transport pumps as well as a number of positive transport channels. With regard to the sodium-potassium pump (which is essentially a carrier protein), it is important to note that it comes in handy in the regulation of the concentration of ion on the cell membrane’s both sides via the movement of potassium ions into the cell, and sodium ions out of the cell (Toole and Toole, 2004). As Kalat notes (2012), outside the membrane, there is often a higher concentration of sodium ions...
References
Kalat, J.W. (2012). Biological Psychology (11th ed.). Belmont, CA: Cengage Learning.
Mushiyakh, Y., Dangaria, H., Qavi, S., Ali, N., Pannone, J. & Tompkins, D. (2012). Treatment and Pathogenesis of Acute Hyperkalemia. J Community Hosp Intern Med Perspect, 1(4), 39-46.
Toole, G. & Toole, S. (2004). Essential A2 Biology for OCR. Cheltenham: Nelson Thornes.
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