Reversing Extinction Without Retraining
Reinstate CS without U.S.
The association between a conditioned stimulus (CS) and an unconditioned stimulus (U.S.) is believed to be the result of synaptic connections that formed during the pairing of the CS and U.S.. Extinction training had therefore been proposed to represent the dissolution of these connections (reviewed in Gupta, Vig, Noelle, 2011). However, a large body of evidence argues against this model and suggests conditioning and extinction represent two functionally distinct neurobiological systems; one for the acquisition of an CS-U.S. association and the other capable of inhibiting this association. This would explain the phenomenon of 'savings', which represents the ability of a response to be restored with little effort after extinction training. The second model also explains why a second round of extinction...
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