The disorder has a prevalence of around 2% to 3% of the population, and this prevalence is likely underestimated in many different countries / and descriptions of obsessions and compulsions have been remarkably consistent over time and place. Neurobiological studies have consistently found evidence that cortical-striatal-thalamic-cortical (CTSC) circuits play a crucial role in mediating the disorder and treatment research has invariably demonstrated that serotonin reuptake inhibitors selectively reduce the symptoms of OCD (Stein, Andersen, & Overo 2007; O'Connor, Todorov, Robillard, Borgeat, & Brault 1999).
The most common treatments for OCD are pharmacological and cognitive behavioral interventions. According to the American Psychiatric Association treatment practice guidelines for OCD, selective serotonin reuptake inhibitors (SSRIs) are considered first-line treatments for OCD. However, SSRIs are often associated with delayed onset of therapeutic effect (8 -- 12 weeks), only partial symptom reduction, and response failure or intolerability in 40% to 60% of patients. Pharmacological options for SSRI refractory cases include increasing drug dose, changing to another SSRI or clomipramine, combining SSRIs, or changing the mode of drug delivery. Augmentation with second-generation antipsychotics has demonstrated efficacy as a second-line treatment (Berlin, Hamilton & Hollander, 2008).Obsessive-compulsive disorder shows a slow, gradual improvement, which starts within a few days after the initiation of treatment and continues for months thereafter. Published consensus guidelines consider an adequate SRI trial in OCD to consist of 10 -- 12 weeks with at least 4 -- 6 at the maximum tolerated dose (Dell'Osso, Altamura, Mundo, Marazziti, & Hollander, 2007).
The addition of typical and atypical antipsychotics in patients with OCD resistant to SRIs has been reported as a useful augmentation strategy. Although antipsychotic mono-therapy has been associated with ineffectiveness and even increase of psychotic symptoms (especially in psychotic patients), antipsychotics as concomitant medications have proven to be effective in several case series and pilot clinical trials. The objective of this case series was to evaluate effectiveness of risperidone as add on therapy to current SRIs treatment in OCD refractory to treatment patients. Results indicated that Risperidone as add on therapy to SRI in moderate-severe, refractory to treatment OCD patients, may be an effective and safe strategy (Arias- Horcajadas, Soto, Garcia-Cantalapiedra, Rodriguez, Morales & Salgado 2006).
It is evident through this compilation...
dysfunctional behavior that strikes 1 out of 40 or 50 adults and 1 out of 100 children or 2-3% of any population. It can begin at any age, although most commonly in adolescence or early adulthood - from ages 6 to 15 in boys and between 20 and 30 in women -- according to the National Institute for Mental Health. This behavioral affliction is, therefore, more common than schizophrenia
These studies show the importance of confronting feared stimuli for extinguishing anxiety. However, at the same time, other research has found that the cognitive methodology has had equal results to the ERP in OCD treatment. Hackman and McLean report that they have as positive results with thought-stopping as those found with ERP. Once again, however, the number of studies has been very small (Abromowitz). It has only been in the
GWA (Genome-Wide Association ) Study Analysis for OCD The OCD (Obsessive Compulsive Disorder) is a type of mental disorder that makes people doing the same thing repeatedly. In other words, the OCD is characterized by unreasonable obsessive fear and thoughts that lead to repetitive behaviors. People suffering from OCD are unable to control their activities and thoughts. While the cause of OCD is unknown, however, the risk factors include stress and
One work specifically isolates a type of treatment that is helpful for ODD or milder CD: In this book our focus is on supportive-expressive play psychotherapy for a particular kind of patient: the school-aged child who meets the criteria for oppositional defiant disorders and mild or moderately severe conduct disorders (DSM-III-R). There are, however, important qualifications. First, the child must demonstrate some capacity for genuine guilt, remorse, or shame about
Clinically meaningful differences between juvenile and adult participants were also found. Compared to adults, juveniles were more likely to be male, recall an earlier age at OCD onset, and have different lifetime comorbidity patterns. Significant outcomes were that children were less likely than either adolescent or adults to report aggressive obsessions and mental rituals. The glaring - and possibly only -- distractions that I see with this study are that
" (p. 12) According to Cromer (2005) the literature that addresses the relationship between stressful life events and obsessive compulsive disorders does provide some degree of support implicating traumatic life-stress as being a factor in the onset and maintenance of the obsessive compulsive disorders however the exact relationship between the SLE and OCD "remains an empirical questions" specifically relating to "traumatic negative life events" (2005; p.13) Most of studies in
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