Mass Spectrometry in Medical Research
Metabolics is an emerging approach to cardiovascular biomarker research. Through the use of metabolic approaches based on chemistry, the metabolic properties that underlie a variety of cardiovascular disease (CVD) states can be analyzed (Senn, et al., 2012). Biomarkers are currently identified in biospecimens according to quantified protein-based end products, rather than representing the disease states by the metabolomics profiles that characterize the disease (Senn, et al., 2012). The literature shows use of both open (unbiased) and closed (targeted) approaches to "identifying, describing, and verifying metabolic differences between disease and nondisease conditions" (Senn, et al., 2012). The use of metabolomics profiling, without evidence of traditional risk factors, is being used to learn more about mortality due to cardiovascular disease, as well as myocardial infarction and stroke (Senn, et al., 2012).
Cardiovascular disease (4-6 sentences are enough)
The leading cause of mortality and morbidity in developed nations is cardiovascular disease (CVD) (Barallobre-Barreiro, et al., 2013). The current state of cardiovascular medicine requires reliance on commonly known and quite well understood conventional risk factors: Age, diabetes, gender, hypertension, and smoking (Barallobre-Barreiro, et al., 2013). A considerable difficulty associated with these risk factors is their prevalence in the general population, which results in high prediction failure rates for a majority of CVD cases over a 10-year period; this is true with even the best available algorithms for acute coronary events (Barallobre-Barreiro, et al., 2013). Moreover,...
Cardiovascular diseases' is an umbrella term representing a number of disorders known to affect the heart and blood vessels. According to the World Health Organization (WHO), the number of deaths attributable to cardiovascular diseases (CVDs) is higher than that attributable to any other disease. However, people who live in low-income nations are more prone to death from CVDs than those who live high-income nations. People in Low-Income Countries More Likely to
Nuances in Exercise and Cardiovascular Disease: A Comprehensive Approach for Men\'s Health Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality among men worldwide. Regular physical activity is widely recognized as a protective factor against various forms of CVD, including coronary artery disease, heart failure, and hypertension (Myers, 2003). Nevertheless, the relationship between exercise and CVD in men is complex, with nuances that are critical to understand. Engaging in
Cardiovascular diseases are one of the major public health concerns since they contribute to 7 million hospitalizations annually and death. As a result, the identification of suitable treatment options for the diseases is important in order to enhance patient outcomes. Advanced practice nurses play a critical role in recommending appropriate treatment options for patients with these disorders. This process entails examining aspects that could influence the patient’s pharmacokinetic and pharmacodynamic
Metabolic syndrome is significant for our patient for several reasons. As we have noted, the syndrome is associated with a higher risk of cardiovascular disease. Those patients who have metabolic syndrome tend to develop coronary atherosclerosis at a higher rate than those who have coronary risk factors alone. Obesity increases the risk of metabolic syndrome but so does pre-obesity, or BMI ranging from 25-30. Women who have been diagnosed with
"Participants were instructed to drink no more than 3 caffeinated beverages and no more than 2 alcoholic beverages per day" (pg. 2457). Two features from this study that stand out when compared to the previous study (as read about earlier) was that this study sought to keep the participants weight relatively stable and that the participants were not obese and old, but were young and healthy. The goal of this
The first heart sound is generally longer and lower than the second, producing a heartbeat that sounds like lub-dup, lub-dup, lub-dup. Blood pressure, the pressure exerted on the walls of blood vessels by the flowing blood, also varies during different phases of the cardiac cycle. Blood pressure in the arteries is higher during systole, when the ventricles are contracting, and lower during diastole, as the blood ejected during systole moves
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