Medication Compliance in Psychotic Disorders
Janssen, Birgit., Gaebel, Wolfgang., Haerter, Martin, Komaharadi, F., Lindel, Birgit., & Weinmann, Stefan. (2006 April). "Evaluation of factors influencing medication compliance in inpatient treatment of psychotic disorders. Psychopharmacology 187:229-236.
The authors and researchers examine short- and long-term compliance to prescribed antipsychotic drugs. Their objective is to evaluate patient-related and treatment-related factors associated with medication compliance in inpatients with the following diagnoses: schizophrenia, schizoaffective disorder, and other psychotic disorders. The study is a "naturalistic study," based in seven hospitals with patients assessed weekly. The following characteristics were studied: social function, side-effects of medication, mental status, and compliance to medication requests. The researchers in this study attempted to determine whether medication is the basis for compliance or whether multiple factors including innate factors such as social influence and individual characteristics, environmental characteristics, genetic and personality characteristics were more likely to influence medication compliance in psychotic patients because medication compliance is so low among psychotic patients. Previous research suggests that medication compliance has less to do with medication alone and more to do with a combination of factors including traits associated with the psychosis of the patient.
The researchers in this study used logistic regression analysis to measure medication compliance. The results of the study showed a clear association between patient's compliance with orders and substance abuse and involuntary admission and compliance. Also relevant were...
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