Mechanisms of Aging
Mechanism of Aging
Aging is a syndrome that occurs as a result of changes that are progressive, deleterious, universal and therefore, irreversible. This aging damage occurs to the cells, molecules that forms the cells, and to the entire organ. The aging process is most commonly associated with old age diseases such as osteoporosis, arthritis, cancer, heart disease and Alzheimer's disease among others; this is because such diseases are associated with degenerative effects experienced by the cells. Scientist have over the years substituted the word "aging" with "senescence" since aging means that when time elapses so does deterioration takes place which is false especially during the early developmental stage Mackenzie, Bussiere and Tinsley ( 21)
Various researches are being conducted to establish the mechanisms of aging, and as part of these research, experiments have been carried out on various living organism so as to shade more light on this concept. These organism include; humans, rodents, flies, worms and hydra. The criteria used to indicate senescence in these living organisms include;
The fruit flies (Drosophila melanogaster ) and the nematode worms (Caenorhabditis elegans ) are the most common invertebrate species used in biological experiments since on reaching maturity both species are composed post-mitotic cells, except for the germ line.
Flies (Drosophila) have been found to have a natural antioxidant enzyme SuperOxide Dismutase (SOD) & CATalase (CAT), but no glutathione peroxidase Comfort
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