In CML, "the leukemia cell that starts the disease makes blood cells (red cells, white cells and platelets) that function almost like normal cells" (Leukemia and Lymphoma, 2010). Moreover, the number of red cells usually declines in CML, which causes anemia (Leukemia and Lymphoma, 2010). CML does not tend to reduce the number of white cells or platelets, and their performance remains somewhat normal, however their counts are high and can continue to rise, causing health complications (Leukemia and Lymphoma, 2010). If white blood counts rise too high, blood flow can slow down, causing severe anemia (Leukemia and Lymphoma, 2010). In CLL, the leukemia cell makes lymphocytes that do not function properly, instead, "the leukemia cell that starts the disease makes too many lymphocytes that do not function. These cells replace normal cells in the marrow and lymph nodes. They interfere with the work of normal lymphocytes, which weakens the patient's immune response" (Leukemia and Lymphoma, 2010). As in CML, the high number of leukemic cells can crowd out the number of normal cells, leading to anemia. However, CLL can also result in "low neutrophil and platelet counts" (Leukemia and Lymphoma, 2010). However, CLL does not tend to cause the out-of-control growth of white blood cells, so it generally does not have the immediate negative health impacts of the other three types of leukemia. Instead, some patients diagnosed with CLL may not require immediate treatment and may not notice any impact on their health or well-being for a significant...
Moreover, the four main types of leukemia have different subtypes. In addition, a patient's personal characteristics, including age and overall health, can help determine the appropriate treatment plan. The goal of treatment for leukemia is complete remission, rather than simply increasing life expectancy. Therefore, patients with acute leukemia begin immediate treatment, usually radiation and/or chemotherapy in a hospital setting, with the goal of reducing the number of leukemic cells. After induction therapy, patients receive follow-up care that includes inpatient chemotherapy and may include stem cell transplants. CML patients have a different type of therapy. Generally, they are given drugs like Gleevec, which can suppress the gene responsible for the CML, thus eliminating symptoms, though not curing the CML. Stem cell transplantation is the only currently known cure for CML, and is more successful in younger patients. CLL patients may not need immediate treatment. When they do need treatment, chemotherapy, monoclonal antibody therapy, and stem cell transplants are all viable treatment options (See generally Leukemia and Lymphoma, 2010).
Bone Marrow Advocacy Bethematch.org is the website for the National Bone Marrow Donor Program. Through the website and the Be the Match organization, people can register to become potential bone marrow donors. Be the Match is the central bone marrow donation registry for the United States. It is a non-profit organization, and it works with doctors, patients, and donors to help match recipients. It does not provide compensation to donors and
Blood Diseases and Disorders There are dozens of blood diseases and disorders with the blood disorders affecting any of the three major components of the blood. These three components of the blood include red blood cells (carry oxygen to the body's tissues), white blood cells (fight infections), and platelets (assist blood to clot). Additionally, blood disorders can affect plasma, which is the liquid segment of the human blood. The diagnosis and
Conclusion Despite the depressing figures embodied in the quote introducing this thesis, that: "The overall cure rate for AML…is between 40 and 45%" (Belson, Kingsley, and Holmes, para. 6), data/information related during the next chapter, the Literature Review, will contain a semblance of hope. Hope for the potential development of significant improvement of therapies for AML, the researcher projects, albeit, depends on continuing studies such as the three noted in/by this
The authors did a comparison study of 682 adults with acute leukemia. All these patients received a hematopoietic stem-cell (HSC) transplant from a donor that was unrelated to them. The authors compared them to patients who received UCB instead of HSC. One of the important characteristics of UCB is that it does not have to match the donor, which makes it much more flexible in leukemia and other treatments. The study
diseases i.e. lung cancer, childhood leukemia, obesity and Alzheimer's disease. In each explanation, I have included a definition of the disease, risk factors, treatments, prognosis, and prevention. Later, I have provided short literature reviews of four articles. Lung Cancer Lungs are those organs in the body that help the human beings to breathe i.e. inhale and exhale oxygen. Their primary function is to provide oxygen to every cell in the body.
Chronic Myelogenous Leukemia (CML): Treatment Options Patients suffering from chronic myelogenous leukemia (CML) experience recurrent infections, anemia, and thrombocytopenia, signs and symptoms often manageable without professional help. Accordingly, patients often failed to seek medical care until late in the disease course and would have had a poor prognosis in the 20th century. Today, a number of effective treatments are available, including the highly effective kinase inhibitor imatinib. Kinase inhibitors suppress the
Our semester plans gives you unlimited, unrestricted access to our entire library of resources —writing tools, guides, example essays, tutorials, class notes, and more.
Get Started Now