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Kidney Donation And Renal Availability: Thesis

"UK sees rise in people donating a kidney to unknown recipients." British medical journal 338(7710), pp. 1521. In this brief yet highly relevant article, the author describes a recently observed trend of increasing live-donor kidney donations for unknown recipients. Though living donors for family members with a need for transplant have been relatively common for sometime, the idea of donating a kidney while still living for a person unknown to the donor is a very recent development in kidney translation and availability. Though the reasons for this increase are not yet clear, as no research has been undertaken to determine the causal effect of this observed trend, initial results suggest that simple awareness of the need for renal donation and the normalcy of life following the donation of a kidney is a major factor.

Nakamura, Y.; Konno, O.; Matsuno, N.; Yokoyama, T., et al. (2008). "How can we increase living related donor renal transplantations?" Transplantation proceedings 40(7), pp. 2104-7.

Though various methods and schema for renal transplantation exist, this study points out the benefits of living donor donation in the combating of end-stage renal failure, in Japan specifically. Citing a decreased need for recipient medication and an increased likelihood...

A new surgical procedure developed by the authors limits the invasiveness and the blood loss in an elective living donor surgery, and combined with higher donorship rates could greatly increase the successful treatment of renal disease.
Testa, G.; Angelos, P.; Crowley-Matoka, M. & Siegler, M. (2009). "Elective surgical patients as living donors: A clinical and ethical innovation." American journal of transplantation 9(10), pp. 2400-5.

An innovative new schema for encouraging organ donation is put forth in this article. Specifically, the authors suggest that patients slated for laporoscopic cholecystectomy be given the opportunity to undergo a more invasive surgical correction and donate a kidney as a living donor at the same time. This would eliminate (or greatly reduce) the need for living donors to become surgical candidates with no health benefit to them; the same surgery and level of invasiveness would both correct the patients' problem and allow for donorship. This is the reverse of the current living donor schema, in which donors become surgical candidates specifically for…

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Though various methods and schema for renal transplantation exist, this study points out the benefits of living donor donation in the combating of end-stage renal failure, in Japan specifically. Citing a decreased need for recipient medication and an increased likelihood of successful transplantation when kidneys used in transplantation come from living donors, the authors of this study examine various methods for increasing rates of living donorship. A new surgical procedure developed by the authors limits the invasiveness and the blood loss in an elective living donor surgery, and combined with higher donorship rates could greatly increase the successful treatment of renal disease.

Testa, G.; Angelos, P.; Crowley-Matoka, M. & Siegler, M. (2009). "Elective surgical patients as living donors: A clinical and ethical innovation." American journal of transplantation 9(10), pp. 2400-5.

An innovative new schema for encouraging organ donation is put forth in this article. Specifically, the authors suggest that patients slated for laporoscopic cholecystectomy be given the opportunity to undergo a more invasive surgical correction and donate a kidney as a living donor at the same time. This would eliminate (or greatly reduce) the need for living donors to become surgical candidates with no health benefit to them; the same surgery and level of invasiveness would both correct the patients' problem and allow for donorship. This is the reverse of the current living donor schema, in which donors become surgical candidates specifically for donor purposes, raising ethical and medical concerns.
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