Introduction
Huntington’s disease is one of many neurodegenerative diseases, which has chorea as one of its prevalent symptoms (Hergert, Sanchez-Ramos, & Cimino, 2019, p.1) . Discovered in the late 1800s’ by George Huntington, a young American medical doctor at the time, the disease has gathered interest from the medical community—but with little in the way of a cure. The disease is highly hereditary, with a 50% chance of transference from parent to offspring (Boyle, Frölander & Manley, 2008, p.333; Roos, 2010, p.6). This hereditary property (of this disease) is due to it being a genetic disorder, which is activated in those that exhibit its symptoms. Primarily, every person has the gene that causes Huntington’s disease, and the activation is equally likely in both biological classifications of human gender (Male and Female); however, those that activate its activity have the expanded version of the gene. For those with the defective gene, the onset of the disease is usually around ages of 30-40 years; however, using medical imaging techniques, its manifestation can be predicted up to 15 years before its onset (Petersén & Weydt, 2019, p.179). Considering the fatality of this disease and its accompanying effects, patients suffering from it usually die of either pneumonia or suicide (Roos, 2010, p.2). In the exploration of this disease, this paper considers its consequence on oral histology and embryology. Also, its pathogenesis and effects on the human immune system is examined.
Oral Histology and embryology
These describe...
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