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What Human Genome Sequences Tell Us Term Paper

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Human Genome Sequencing

The Human Genome Project has shown us that, despite our many differences, we are all fundamentally the same. We share 99.9% of our DNA with every other human being on the planet. This clear evidence of our shared humanity should remind us of our common bonds and our responsibility to care for one another. The one humanity, many genomes project is an important step in furthering this understanding. By sequencing the genomes of people from all over the world, we can learn more about our shared history and the genetic diversity that makes us unique (Kidd et al., 2012). This knowledge can help us to develop new treatments for diseases, and to create policies that protect the rights of all people, regardless of their ancestry. In a world that is increasingly divided, the one humanity, many genomes project is a powerful reminder of our common humanity.

So what makes our genome unique? One example is sequence variation: small differences in the order of the nucleotides that make up our DNA. These variations can affect the way a gene is expressed and, as a result, influence phenotypic traits like hair and eye color. Another example of variation is copy number variation (CNV),...

…become increasingly commonplace, providing us with valuable insights into our own health and that of our families.

Additionally, as a pharmacy healthcare professional, I am very excited about the potential implications for my future career. As we learn more about the role of genetics in health and disease, we will be able to develop targeted therapies that are more effective and have fewer side effects. In addition, we will also be able to screen patients more accurately for genetic conditions, allowing us to provide tailored care and support. The advances in genomic research are truly transformative, and I am incredibly excited to see what…

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References

Kidd, J. M., Gravel, S., Byrnes, J., Moreno-Estrada, A., Musharoff, S., Bryc, K., ... &Bustamante, C. D. (2012). Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. The American Journal of Human Genetics, 91(4), 660-671.

Mills, R. E., Walter, K., Stewart, C., Handsaker, R. E., Chen, K., Alkan, C., ... & Korbel,J. O. (2011). Mapping copy number variation by population-scale genome sequencing. Nature, 470(7332), 59-65.

Wade, C. H., Tarini, B. A., & Wilfond, B. S. (2013). Growing up in the genomic era:implications of whole-genome sequencing for children, families, and pediatric practice. Annual Review of Genomics and Human Genetics, 14, 535.

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