Pharmacotherapy for Hematologic Disorders
Anemia is an hematologic disorder that occurs when the individual lacks the requisite number of healthy red blood cells for bringing oxygen to the bodys cells. Without oxygen, the bodys cells are essentially choked to death. Red blood cells depend on a number of supports, such as iron, B12, and folate for healthy development. In children these supports are especially necessary and they are still in a developmental stage. Treating children with anemia can depend upon the severity and source causing the anemia; however, there are some pharmacotherapy options available. This paper will consider drug treatments for patients with anemia and the factor of age and how it plays a part in the treatment process.
As Ozdemir (2015) notes, reduced erythrocyte count or a hemoglobin (Hb) value 5 percentile below the normal hemoglobin value specified for that age in healthy individuals is defined as anemia (p. 11). Treating this condition, then, requires a drug that can address the issues in the blood without harming the individuals development, which is an especially important factor because of the age of the patient. Because there are many different types of anemia, such as iron deficiency anemia to sickle cell anemia, to hemolytic anemia, to congenital sideroblastic anemia, it is...
…hemoglobin concentration at 12 weeks. Once daily, low-dose ferrous sulfate should be considered for children with nutritional iron-deficiency anemia (p. 2297). Reducing side effects for the treatment would require taking time off from treatment, or switching approaches while the child is still strengthening the body through supplements and blood transfusions if necessary. The approach identified by Powers et al. (2017), however, would help to restore the childs hemoglobin concentration over a relatively short period of time3 months at mostand all that this would require is a one-time a day treatment of ferrous sulfate, which should not have a negative side effect on the child to…
References
Özdemir, N. (2015). Iron deficiency anemia from diagnosis to treatment inchildren. Turkish Archives of Pediatrics/Türk Pediatri Ar?ivi, 50(1), 11.
Powers, J. M., Buchanan, G. R., Adix, L., Zhang, S., Gao, A., & McCavit, T. L. (2017).
Effect of low-dose ferrous sulfate vs iron polysaccharide complex on hemoglobin concentration in young children with nutritional iron-deficiency anemia: a randomized clinical trial. Jama, 317(22), 2297-2304.
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