¶ … Childhood Trauma and Risk for Chronic Fatigue Syndrome: Association with Neuroendocrine Dysfunction." Heim, C., Nater, U.M., Maloney, E., Boneva, R., Jones, J.F., & Reeves, W.C.
What did the researchers want the study to determine?
The researchers wanted to determine if there was a correlation between childhood trauma and the eventual development of chronic fatigue syndrome (CFS) by examining neuroscience and looking for evidence related to the pathophysiology of the disease.
Health Outcome of Interest: What health condition did the researchers study?
The researchers studied chronic fatigue syndrome.
Exposure(s) of Interest: What factors did the researchers investigate to determine an association with the outcome listed above? There may be more than one.
Researchers looked at patients with childhood trauma and those with CFS. They looked at the neuroendocrine system including the hypothalamic-pituitary-adrenal axis and other neurodendocrine dysfunctions.
5. Participants: Whom did the researchers study? How many?
113 patients with CFS and 124 control patients were surveyed from a population of 19,381 Georgian resident adults.
6. Study design: What type of epidemiological study design -- observational or experimental -- does the study describe? Why?
This was an experimental study in that measurements of saliva were taken but also observational based...
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